Brian M. Dudley, Ph.D., is counsel in Sterne Kessler's Biotechnology & Chemical Practice Group. Brian primarily assists in the preparation and prosecution of U.S. and foreign patent applications and preparation of opinions of counsel. Brian's professional expertise includes genetics, molecular biology, biochemistry, immunology, stem cell biology, developmental biology, and microbiology.
While earning his Ph.D. from Case Western Reserve University, Brian characterized the role of Bone Morphogenetic Proteins (BMPs) in establishing a primordial germ cell niche in the early mouse embryo. Brian found that BMP signaling promotes the survival of niche somatic cells and the expression of germ cell survival factors and potential migrational cues.
As a law student at American University Washington College of Law, Brian served as a member of the American University Law Review, the senior articles editor of the Intellectual Property Brief, and a student attorney with the Glushko-Samuelson Intellectual Property Law Clinic. Brian received his B.A. in biochemistry and molecular biology from the College of Wooster.
Technical Publications
- Dudley, B., Molyneaux, K. (2011). In vivo germ line stem cell migration: a mouse model. Methods Mol. Biol. 750:117.
- Dudley, B., Palumbo, C., Nalepka, J., Molyneaux, K. (2010). BMP signaling controls formation of a primordial germ cell niche within the genital ridges. Developmental Biol. 343:84.
- Ding, J., Jiang, D., Kurczy, M., Nalepka, J., Dudley, B., Merkel, E., Porter, F.D., Ewing, A.G., Winograd,N., Burgess, J., Molyneaux, K. (2008). Inhibition of HMGCoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse. BMC Developmental Biol.;8(1):120.
- Dudley, B.M., Runyan, C., Takeuchi, Y., Schaible, K., Molyneaux, K. (2007). BMP signaling regulates PGC numbers and motility in organ culture. Mechanisms of Development;124(1):68.