Yunjun “June” Guo, Ph.D., is an associate in Sterne Kessler’s Biotechnology & Chemical Practice Group. She assists in the preparation and prosecution of U.S. and foreign patent applications and in the preparation of freedom to operate and patentability opinions. She also assists in inter partes review proceedings. June’s primary areas of technical expertise include antibody-drug conjugates, molecular imaging, pharmaceutical chemistry, and cancer biology.
June performed her graduate research at Washington University School of Medicine. Her research focused on developing receptor-targeting radiopharmaceuticals for cancer imaging and therapy. June developed a novel therapeutic regimen that combines chemotherapy with EGFR-targeting radio-immunotherapy to overcome the drug resistance of KRAS-mutated colorectal cancer. This research was reported by MolecularImaging.net as “promising for genetically mutated colorectal cancer.” June also studied the interrelationships of Atox1, KRAS and p53 in drug resistant colorectal cancer and the implications for cancer therapy. While in graduate school, June received the U.S. Department of Energy Pre-doctoral Traineeship Award and the American Chemical Society DOE Award. She was also the recipient of two student awards from the Society of Radiopharmaceutical Sciences and the International Symposium of Radiopharmaceutical Sciences.
Prior to law school, June served as the licensing assistant in the technology transfer office of a research university. There, she assisted and advised faculty in protecting and commercializing university intellectual property. She also supported university spin-offs in scientific and legal affairs with the NSF I-Corps Site Program.
As a law student, June represented the University of Akron School of Law in the 2016 AIPLA Giles Sutherland Rich Moot Court Competition. June has been an active member in the IP-in-China Committee of the AIPLA. She was the first student delegator of the AIPLA’s Annual Delegation Trip to China. Prior to joining Sterne Kessler, June worked at a boutique intellectual property law firm in Cleveland, OH where she assisted with patent prosecution.
- Guo, Y., Parry, J., Laforest, R., Rogers, B., Anderson, C.. The role of p53 on combination radioimmunotherapy with 64Cu-DOTA-cetuximab and cisplatin in a mouse model of colorectal cancer, Journal of Nuclear Medicine 2013; 54(9):1621-29 (Featured by MolecularImaging.net).
- Guo, Y., Aweda, T., Black, K., Liu, Y.. Chemistry and Theranostic Applications of Radiolabeled Nanoparticles for Cardiovascular, Oncological, and Pulmonary Research, Current Topics in Medicinal Chemistry 2013; 13(4): 470-78.
- Guo, Y., Ferdani, R., Anderson, C.. Preparation and biological evaluation of 64Cu labeled Tyr3-Octreotate using a phosphonic acid derivative of cross-bridge cyclam as the chelator, Bioconjugate Chemistry 2012; 23(7):1470-77.
- Zeng, D.*, Guo, Y.*, White, A., Cai, Z., Modi, J., Ferdani, R., Anderson, C.. Comparison of Conjugation Strategies of Cross-bridged Macrocyclic Chelators with Cetuximab for Copper-64 Radiolabeling and PET Imaging of EGFR in Colorectal Tumor-bearing Mice, Molecular Pharmaceutics 2014; 11(11): 3980–87 (*equal contribution).
- Beaino, W., Guo, Y., Chang A., Anderson, C.. Roles of Atox1 and p53 in the trafficking of copper-64 to tumor cell nuclei: implications for cancer therapy, Journal of Biological Inorganic Chemistry 2014; 19(3): 427-38.
- Guo, Y., Zheleznyak, A., Anderson, C.. Relationship between Cisplatin, Copper-64 Radiopharmaceuticals and p53 in the trafficking of 64Cu to the nuclei of tumor cells, Proceedings of Technetium and Other Radiometals in Chemistry and Medicine 2010.
- Ferdani, R., Guo, Y., Stigers, D., Fiamengo, A., Wei, L., Golen, J., Rheingold, A., Wong, E., Weisman, G., Anderson, C., Cu(II) Complexation, 64Cu-Labeling and Biological Evaluation of CB-TE1A1P, Proceedings of Technetium and Other Radiometals in Chemistry and Medicine 2010.
- Zheng, P.*,Guo, Y.*,Liu, W., Li, Y., Zuo, J., You, X.. Syntheses, crystal structures, and electrochemical properties of transition metal complexes with new tetrathiafulvalene-derivatizedacetylacetonate ligands, Transition Metal Chemistry 2008, 33(6), 767-73 (*equal contribution).
- Liu, W., Guo, Y., Li, Y., Mao, Y., Zuo, J., You, X.. New fluorescent benzocrown ether derivatives of tetrathiafulvalene: facile synthesis and recognition properties, Research on Chemical Intermediates 2008, 34(2-3), 257-66.
- Liu, W., Guo, Y., Zeng, X., Zuo, J., You, X.. Synthesis, Electrochemical studies and Crystal Structures of New Unsymmetrical TetrathiafulvaleneCaboxylate Derivatives, Journal of Heterocyclic Chemistry 2007, 44(4), 831-36.
- AIPLA, IP-in-China Committee